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Infectious Disease: COVID-19
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Canadian Physiotherapists Integrate Virtual Care during the COVID-19 Pandemic
CONCLUSIONS: Canadian physiotherapists exhibited high adaptability in response to COVID-19 through the rapid and widespread use of virtual care. By creating an in-depth understanding of the barriers and enablers to virtual care, along with potential interventions, this work will facilitate future opportunities to support and enhance physiotherapists' delivery of virtual care.PMID:37736382 | PMC:PMC10510558 | DOI:10.3138/ptc-2022-0092
Source: Physiotherapy Canada - September 22, 2023 Category: Physiotherapy Authors: Allison M Ezzat Jean-Francois Esculier Sarah Lord Ferguson Christopher Napier Sabrina T Wong Source Type: research
ASO Visual Abstract: De-Implementation of Low-Value Care in Women ≥ 70 Years with Low-Risk Breast Cancer During the COVID-19 Pandemic
Ann Surg Oncol. 2023 Sep 21. doi: 10.1245/s10434-023-14329-y. Online ahead of print.NO ABSTRACTPMID:37735322 | DOI:10.1245/s10434-023-14329-y
Source: Ann Oncol - September 22, 2023 Category: Cancer & Oncology Authors: Ton Wang Christina Weed Joshua Tseng Alice Chung Marissa K Boyle Farin Amersi Jaswinder Jutla Amin Mirhadi Armando E Giuliano Source Type: research
Did COVID-19 Change the Availability and Use of Clean Energy for Cooking? Evidence From Ghana
This study provides insights that could be valuable in future understanding of the interactions between pandemic control measures and economic disruptions that may affect household energy choices for cooking.PMID:37736574 | PMC:PMC10510355 | DOI:10.1177/11786302231198854
Source: Environmental Health Insights - September 22, 2023 Category: Environmental Health Authors: Rebecca Kd Prah Darby Jack Theresa Tawiah Seidu Iddrisu Sulemana Watara Abubakari Mohammed Nuhu Mujtaba Richard Joshua Tetteh Stephaney Gyaase Mieks Twumasi Jason Saah Joseph Wilson Sheila Addo Daniel Pope Kwaku Poku Asante Elisa Puzzolo Source Type: research
Effects of Photobiomodulation Therapy on Lung Function and Inflammatory Factors in Patients with COVID-19 During Acute Stage
Conclusions: Application of photobiomodulation is recommended for treatment of respiratory problems in patients with COVID-19 to improve clinical signs and control inflammatory factors. Clinical Trial Registration: IRCT2017070934969N1.PMID:37738370 | DOI:10.1089/photob.2022.0157
Source: Cancer Control - September 22, 2023 Category: Cancer & Oncology Authors: Fatemeh Ehsani Rasool Bagheri Mahbubeh Darban Maral Hemati Mohammad Bahrami Fatemeh Sharafieh Source Type: research
Regulatory circuits of mitophagy restrict distinct modes of cell death during memory CD8 < sup > + < /sup > T cell formation
Sci Immunol. 2023 Sep 29;8(87):eadf7579. doi: 10.1126/sciimmunol.adf7579. Epub 2023 Sep 22.ABSTRACTMitophagy, a central process guarding mitochondrial quality, is commonly impaired in human diseases such as Parkinson's disease, but its impact in adaptive immunity remains unclear. The differentiation and survival of memory CD8+ T cells rely on oxidative metabolism, a process that requires robust mitochondrial quality control. Here, we found that Parkinson's disease patients have a reduced frequency of CD8+ memory T cells compared with healthy donors and failed to form memory T cells upon vaccination against COVID-19, highli...
Source: Cancer Control - September 22, 2023 Category: Cancer & Oncology Authors: Fabien Franco Alessio Bevilacqua Ruey-Mei Wu Kung-Chi Kao Chun-Pu Lin Lor ène Rousseau Fu-Ti Peng Yu-Ming Chuang Jhan-Jie Peng Jaeoh Park Yingxi Xu Antonino Cassotta Yi-Ru Yu Daniel E Speiser Federica Sallusto Ping-Chih Ho Source Type: research
Telehealth as an Effective Care Delivery Method During the COVID-19 Pandemic for the Rhode Island Behavioral Health Population
This study investigated (1) if telehealth allowed for patients who seek mental health services to maintain visit frequency and (2) if subpopulations were less likely to utilize telehealth. We used descriptive statistics to analyze the change in total number of visits, in-person visits from pre-waiver to post-waiver, and a multivariate linear regression to identify relationships between demographics and telehealth utilization. Participants were able to maintain the frequency of visits during the COVID-19 pandemic. Race/ethnicity, age, gender, employment status, and housing status were all statistically significant predictor...
Source: Community Mental Health Journal - September 22, 2023 Category: Psychiatry Authors: Demetria Flowers Emily Goodspeed Mackenzie Daly Source Type: research
Therapeutic benefits of prophetic medicine remedies in treating hematological diseases (A review article)
Am J Blood Res. 2023 Aug 15;13(4):130-142. eCollection 2023.ABSTRACTHematological disorders are common medical ailments constituting an important cause of morbidity and mortality worldwide, which may be managed efficiently using different prophetic medicine remedies as adjuvants to current therapeutics. Prophetic medicine includes the body of knowledge about medicine that has been derived from the deeds, customs (sunnah), ahadith (sayings), actions, and agreements of Prophet Muhammad, peace be upon him. This review article aims at exploring the magnitude of therapeutic benefits of prophetic medicine remedies as adjuvant tr...
Source: Cell Research - September 22, 2023 Category: Cytology Authors: Ghazi H Mogharbel Ahmad S Badawi Amal Yaseen Zaman Mehrevan M Abd Elmoniem Ibrahim M Abdel-Rahman Mariam Eid Alenazi Fareed Akbar Shah Mohamed Abdelnaem Aly Syed Nazar Imam Nusaybah Eid Alenazi Salah Mohamed El Sayed Source Type: research
Clinical features and mutational analysis of X-linked agammaglobulinemia patients in Malaysia
ConclusionThis report provides the first overview of demographic, clinical, immunological and genetic data of XLA in Malaysia. The combination of flow cytometric assessment and BTK genetic analysis provides a definitive diagnosis for XLA patients, especially with atypical clinical presentation. In addition, it may also allow carrier detection and assist in genetic counselling and prenatal diagnosis.
Source: Frontiers in Immunology - September 22, 2023 Category: Allergy & Immunology Source Type: research
Case Report: A rare case of non-small cell lung cancer with STRN-ALK fusion in a patient in very poor condition treated with first-line ensartinib
Several cases of STRN-ALK fusion have been reported, and some anaplastic lymphoma kinase (ALK) inhibitors have been shown to be effective for treatment. Nevertheless, no cases of COVID-19 leading to heart failure and respiratory failure have been reported in people older than 70 years treated with ALK inhibitors. The present case report describes a 70-year-old patient with usual chronic obstructive pulmonary disease, diabetes, depression, and carotid plaque disease. Next-generation sequencing of tissue obtained by puncture biopsy revealed a STRN-ALK mutation accompanied by a TP53 mutation. The patient was treated with ensa...
Source: Frontiers in Oncology - September 22, 2023 Category: Cancer & Oncology Source Type: research
Viruses, Vol. 15, Pages 1976: Extracellular Vesicles as a Translational Approach for the Treatment of COVID-19 Disease: An Updated Overview
a Di Domenico
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) caused a global pandemic in the years 2020&ndash;2022. With a high prevalence, an easy route of transmission, and a long incubation time, SARS-CoV-2 spread quickly and affected public health and socioeconomic conditions. Several points need to be elucidated about its mechanisms of infection, in particular, its capability to evade the immune system and escape from neutralizing antibodies. Extracellular vesicles (EVs) are phospholipid bilayer-delimited particles that are involved in cell-to-cell communication; they contain biological infor...
Source: Viruses - September 22, 2023 Category: Virology Authors: Enrica Serretiello Andrea Ballini Annafrancesca Smimmo Marina Acunzo Mariarosaria Raimo Stefania Cantore Marina Di Domenico Tags: Review Source Type: research
Viruses, Vol. 15, Pages 1975: Alterations in Patients & rsquo; Clinical Outcomes and Respiratory Viral Pathogen Activity following the COVID-19 Pandemic
Conclusions: We have demonstrated a reduction in the detection of several viruses, which might be due to the increase in public awareness toward infection protection measures after the COVID-19 pandemic.
Source: Viruses - September 22, 2023 Category: Virology Authors: Khaled Al Oweidat Ahmad A. Toubasi Ahmad Alghrabli Yasmeen Khater Noor Saleh Asma S. Albtoosh Rawan Shafeek Batarseh Tags: Article Source Type: research
SARS-CoV-2 egress from Vero cells: a morphological approach
This study aimed to shed light on the morphological features of SARS-CoV-2 egress by utilizing transmission and high-resolution scanning electron microscopy, along with serial electron tomography, to describe the route of nascent virions towards the extracellular medium. Electron microscopy revealed that the clusters of viruses in the paracellular space did not seem to result from collective virus release. Instead, virus accumulation was observed on incurved areas of the cell surface, with egress primarily occurring through individual vesicles. Additionally, our findings showed that the emission of long membrane projection...
Source: Histochemistry and Cell Biology - September 22, 2023 Category: Biomedical Science Source Type: research
Biogeographical Impacts of Dental, Oral, and Craniofacial Microbial Reservoirs
J Dent Res. 2023 Sep 20:220345231191115. doi: 10.1177/00220345231191115. Online ahead of print.ABSTRACTThe human mouth, or oral cavity, is at the crossroads of our external and internal environments, and it is increasingly evident that local colonization of dental, oral, and craniofacial (DOC) tissues and cells by bacteria and viruses may also have systemic effects across myriad diseases and disorders. Better understanding of this phenomenon will require a holistic understanding of host-microbial interactions in both spatiotemporal and biogeographical contexts while also considering person-, organ-, tissue-, cell-, and mol...
Source: Cell Research - September 21, 2023 Category: Cytology Authors: Q T Easter B Fernandes Matuck B M Warner K M Byrd Source Type: research
Bioactive lipid-based therapeutic approach to COVID-19 and other similar infections
Arch Med Sci. 2021 Apr 23;19(5):1327-1359. doi: 10.5114/aoms/135703. eCollection 2023.ABSTRACTCOVID-19 is caused by SARS-CoV-2 infection. Epithelial and T, NK, and other immunocytes release bioactive lipids especially arachidonic acid (AA) in response to microbial infections to inactivate them and upregulate the immune system. COVID-19 (coronavirus) and other enveloped viruses including severe acute respiratory syndrome (SARS-CoV-1 of 2002-2003) and Middle East respiratory syndrome (MERS; 2012-ongoing) and hepatitis B and C (HBV and HCV) can be inactivated by AA, γ-linolenic acid (GLA, dihomo-GLA (DGLA), eicosapentaenoic ...
Source: Archives of Medical Science - September 21, 2023 Category: Biomedical Science Authors: Undurti N Das Source Type: research
Our Vocabulary Is Adapting to a Hotter Planet
Discussions of climate change began even before Broecker’s paper, without any of the white-hot rhetoric that has characterized much of our approach to the issue since. In 1973, a team of environmental scientists published a paper in MIT Press under the title “Study of Man’s Impact on Climate.” They labeled that impact “inadvertent climate modification.” The phrasing, while accurate enough, never caught on. NexisLexis counts just 11 uses of the term from 1968 to 2023, with the earliest occurring on Feb. 9, 1988, on a PBS program about math and science education.
“The first test w...
Source: TIME: Science - September 21, 2023 Category: Science Authors: Jeffrey Kluger Tags: Uncategorized climate change healthscienceclimate Source Type: news
